Antibody Peptides as Cancer Vaccine—Turning Weapons to Targets
نویسندگان
چکیده
Abstract Stereotyped B-cell receptors (BCR) are frequent in patients with chronic lymphocytic leukemia (CLL). In cell culture and mouse models of CLL, immunogenic epitopes these BCRs were shown to trigger specific T-cell responses control development. These results suggest vaccination autologous BCR-derived peptides as a novel therapy for CLL. See related article by Rovida et al., p. 729
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2021
ISSN: ['1557-3265', '1078-0432']
DOI: https://doi.org/10.1158/1078-0432.ccr-20-3977